Lisa, a stay-at-home mom, sent her confession to our producers in an email. She wrote, "I am sincerely tired of pretending my life is perfect when in reality I'm in ruins."

Lisa is also a compulsive gambler who hid her addiction from friends and family for months. Just five days ago, she told her family about her double life and is ready to face up to the consequences.

Oprah applauded Lisa's courage in coming forward. "Nobody is insignificant and you are not your mistakes—you made a mistake," Oprah says. "I think the fact that you are here letting the rest of the world know you made a mistake is a very honorable thing to do. The fear you hold is that the people who love you won't love you anymore. The people who love you will still love you."