What is the number one killer of women in America? Breast cancer? Car accidents? In the past 12 months, more women—494,000, to be exact—were killed by cardiovascular disease than by any other cause. In fact, more women will die from cardiovascular disease than from the next six causes combined.

Cardiovascular disease is a wide-ranging problem. "It's the rusting of our arteries," explains renowned surgeon Dr. Mehmet Oz. "Literally, the tubes that carry nourishment to our different organs are rotting from the inside. And that's not just about dying from heart attacks and strokes. It's about kidney failure and loss of quality of life."

Why does coronary artery disease happen? The answer…and more FAQS debunked from Dr. Oz and Dr. Michael Roizen!

Oprah like you've never seen her before. »