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Breast Cancer Diagnosis

Who's Most at Risk for Breast Cancer?

The biggest risk factor for breast cancer is having had breast cancer before. Previous history of breast cancer means a three- to fourfold higher risk of a new cancer in another breast or another part of the same breast, which are considered to be different than a recurrence of previous breast cancer.

You are at moderately high risk of breast cancer if:

  • You're getting older. Your risk for breast cancer increases as you age.
  • You have a direct family history of breast cancer. Having a first-degree relativemother, sister or daughterwho has or had breast cancer puts you at higher risk for the disease. Having one first-degree relative with breast cancer approximately doubles a woman's risk. Having two first-degree relatives increases her risk fivefold.
  • You carry a breast cancer gene mutation. Women with inherited alterations in breast cancer genes called BRCA1 or BRCA2 have up to an 80 percent lifetime risk of breast cancer.
  • You've had previous breast lesions. A previous breast biopsy result of atypical hyperplasia (lobular or ductal) increases a woman's breast cancer risk by four to five times.

As a reminder, always consult your doctor for medical advice and treatment before starting any program.

SOURCES: Sources: WebMD Medical Reference provided in collaboration with Cleveland Clinic: "Breast Cancer: Overview of Risks." WebMD Medical Reference: "Breast Cancer Detection." WebMD Medical Reference provided in collaboration with Cleveland Clinic: "Breast Cancer: Breast Self-Exam." National Cancer Institute: "Breast Cancer PDQ: Screening (Health Professional Version)." WebMD Medical Reference provided in collaboration with Cleveland Clinic: "Breast Cancer: Doctor's Breast Exam." WebMD Medical Reference provided in collaboration with Cleveland Clinic: "Breast Cancer: Mammograms." WebMD Medical News: "New Mammography Guidelines for Women." Qaseem, A. Annals of Internal Medicine; vol. 146: pp. 511-515. Armstrong, K. Annals of Internal Medicine; vol. 146: pp. 516-526. Elmore, J. Annals of Internal Medicine; vol 146: pp 529-532. WebMD Medical Reference provided in collaboration with Cleveland Clinic: "Breast Cancer: Breast MRI." WebMD Medical Reference provided in collaboration with Cleveland Clinic: "Breast Cancer: Breast Biopsy." WebMD Medical Reference provided in collaboration with Cleveland Clinic: "Breast Cancer: Ductal Lavage." WebMD Feature: "What to Do After a Breast-Cancer Diagnosis." American Cancer Society website. National Cancer Institute website. Joan Arnim, manager, patient advocacy program, University of Texas M.D. Anderson Cancer Center, Houston.

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